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A systematic review that investigated the beneficial effects of L-Carnitine supplementation for weight management in overweight and obese adults found that L-Carnitine significantly reduced weight, BMI, and fat mass[2] 2

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Yet, under conditions with aberrations, such as inborn or acquired carnitine deficiency, hemodialysis, or in sarcopenic and frail subjects, supplementation with l-carnitine has been shown to increase physical performance and muscle mass and function