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To understand the underlying mechanisms between SIRT7 and AAA, RNA sequencing of aneurysmal tissues was performed

It may help support the reduction of melanin production, which is responsible for dark spots and uneven skin pigmentation

More importantly, how such metabolic remodeling directly governs the process of N1 polarization in this context is still unresolved, representing a critical knowledge gap on how metabolic regulation is linked to neutrophil inflammatory phenotypes

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Branched amino acids can contribute to energy metabolism as energy source, but the breakdown of these amino acids also replenishes or expands the pool of TCA cycle intermediates that are used as precursors in biosynthetic pathways such as the synthesis of glutathione 54

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