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NAC and NAC + BSO had significantly higher anticancer activity than PBS and BSO

Springer Nature, 2013

Newman SP

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For instance, Artemisinin generates ROS and induces apoptosis while weakly inhibiting GPX4 to trigger mild ferroptosis

therefore we decided to explore its mechanisms in greater depth using the 3D aggregates, a more physiologically-relevant system, and we compared it against the positive control idebenone 41