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Moreover, mounting evidence has demonstrated that genetic depletion of GPx4 can give rise to ferroptosis in an iron-, MEK-, and ROS-dependent manner [30]
Clinical efficacy and quality of life effect of acetylcysteine plus pirfenidone in patients with pulmonary fibrosis

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203 Its pathogenesis is associated with unregulated inflammatory cascades and increased pulmonary endothelial and epithelial cell permeability
