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A large-scale study investigating NAC as an adjunctive therapy for schizophrenia has been conducted,42 which employed a 1000 mg, bi-daily regimen (compared with placebo) in addition to existing medication over 6 months

Deficiencies in other micronutrients, including vitamin B 6 , vitamin B 12 , and omega-3 fatty acids, have been linked to depression, and vitamin D deficiency has also been associated with negative effects on mood (51, 144)

Arch Argent Pediatr2019;117:e420-4.pmid:31339288PubMedGoogle Scholar Corts-Albornoz MC, Garca-Guqueta DP, Velez-van-Meerbeke A, Talero-Gutirrez C

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However, that ratio drops to 10 or less in susceptible cells exposed to oxidative stress