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& Pradhan, A.K

doi: 10.1089/thy.2016.0397 39 BurchHBLahiriSBahnRSBarnesS

1 Introduction Cancer is a complex genetic disease, and multiple genetic and environmental factors have influenced its occurrence and development

43 found that erastin can induce ferroptosis in gastric GC cells and that cysteine dioxygenase type 1 (CDO1) plays a key regulatory role

In addition, we investigated other hallmark genes associated with ferroptosis, including Prostaglandin endoperoxide Synthase 2 (Ptgs2)Acyl-CoA Synthetase Long-Chain Family Member 4 (Acsl4), Ferritin Heavy Chain 1(Fth1) and Transferrin receptor 1 (Tfr1)