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Theoretically yes, since their mechanisms dont overlap 5-Amino-1MQ targets cellular NAD+ metabolism peripherally while tesofensine acts centrally on appetite circuits

A small molecule inhibitor of Nicotinamide N-methyltransferase for the treatment of metabolic disorders (in Eng)

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Advertisement | page continues below Some studies suggest that babies born to women with low levels of vitamin B12 during pregnancy may have an increased risk of neural tube defects

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Eventually fruit and vegetables could be farmed in such a way that their roots, tubers and partly their leaves contain decent amounts of B12 but since it is easier to simply enrich foods there are currently no plans to develop this idea