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Pardi, P
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The allosteric regulators of GLUD1 - ADP, GTP, Leu, NAD + and NADH - exert their effects by changing the energy required to open and close the catalytic cleft during enzymic turnover, in other words by destabilizing or stabilizing, respectively, the abortive complexes
With proper care, the results can last for several months
Increased tonic activation of rat forebrain 5-HT(1A) receptors by lithium addition to antidepressant treatments Neuropsychopharmacology
Hanuska et al
