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A significant portion of half sites is seen in CRPC as well, and enrichment for binding sites for transcription factors, such as HOXB13 is sustained in the cistromes for full-length AR and for ARvs in CRPC [63]

During the rapid regression stage, the child loses purposeful hand skills and spoken language, experiences motor impairments, and develops breathing abnormalities

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Moreover, although preclinical studies have yielded promising results, large-scale, double-blinded clinical trials remain necessary to verify the therapeutic efficacy and feasibility of these approaches in DN patients

Clinical Anatomy Iwanaga J., Wong T.L., Kikuta S., Tubbs R.S