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Coleman et al., 2008

Tony Hale: He does

Kidney diseases, specifically acute kidney injury (AKI) and chronic kidney disease (CKD), represent major global health burdens.3,4 The pathophysiology of these renal diseases involves interconnected mechanisms, notably inflammation, fibrosis, and oxidative stress, with the excessive generation of reactive oxygen species playing a critical role in disease initiation and progression.5,6 Consequently, therapeutic strategies that modulate oxidative stress and associated redox-sensitive signaling pathways are increasingly relevant to nephrological research and clinical practice
M., Bindlish, S., Bonnet, J., Butsch, W

Looking forward, three key research priorities emerge: (1) Mechanistic Elucidation: Future work must precisely define organelle-specific mechanisms, particularly the potential role of lipid droplet-mitochondria cross-talk in airway epithelial cells, and validate these pathways in human COPD samples

Ageing is complex, but with the right tools and strategies, we may be heading into a new era of active, healthy longevity