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Supplied in freeze-dried (lyophilised) form to support long-term storage and controlled research preparation

The stress often associated with food elimination diets can also contribute to histamine release so using a collaborative approach is key

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The PERK/ATF4/CHOP pathway, in particular, emerges as a critical mediator of cochlear cell apoptosis, and its modulation represents a promising therapeutic target

Such different effects of polyphenols enable them to exert biological activity via mechanisms that lead to free radical scavenging, mitochondrial protection, transcription factor regulation, membrane receptor modulation and inhibition of ROS and cellular proliferation [97,98]

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