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The mitochondrial isoform of glutaredoxin (Grx2) is a glutathione-dependent oxidoreductase that is involved in glutathionylation/de-glutathionylation of proteins

Madry, C., Mesic, I., Bartholomaus, I., Nicke, A., Betz, H., and Laube, B., Biochem

A study by Vibhuti et al reported reduced levels of glutathione and low activities of catalase and GXP in COPD patients

J Comp Pathol 2002;126:137-146

Radiat Res 100:115123 Weiss JF, Hoover RL, Kumar KS (1987) Selenium pretreatment enhances the radioprotective effect and reduces the lethal toxicity of WR-2721