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Recent studies suggest that combining NAMPT inhibitors with other therapies could enhance their efficacy and reduce resistance in cancer treatment, as shown in various preclinical animal models 217,218

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[DOI] [PMC free article] [PubMed] [Google Scholar] Kempf S., Popp R., Naeem Z., Frmel T., Wittig I., Klatt S., Fleming I

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Metallothionein is capable of chelating metal ions via sulfhydryl groups to exert metal detoxification [5]

Meal timing: Smaller, more frequent meals help some people handle GI effects during early titration