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[DOI] [PMC free article] [PubMed] [Google Scholar] Mohammad HP, Baylin SB

El-Husseiny and Buchholz 2012)

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Reason for using 2 algorithm-based molecular docking The AutoDock 4.0 software is free and open-source software that utilizes algorithms such as Genetic algorithm , Simulated annealing , and Lamarckian genetic algorithm which makes the protein act as rigid, and the ligand acts as flexible, the scoring functions depend on the empirical free energy function which includes hydrogen, electrostatics and desolvation energies which include poor accuracy for the binding energy

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Identification of anti-inflammatory constituents in Hypericum perforatum and Hypericum gentianoides extracts using RAW 264.7 mouse macrophages