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ChemMedChem 2008, 3, 619626

Pitfalls of Standard Intraocular Pressure-Lowering Drugs On the other hand, the proposed cytoprotective principle of BPC 157 therapy in glaucoma [11] may overwhelm principles commonly acknowledged for potent and efficacious intraocular pressure-lowering drugs

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Nature 461 , 908915 (2009)

Thus, luteolins mechanisms of action on fibroblasts include inhibition of NF-B activation, which is crucial for inflammatory responses [244], and modulating MAPK and PI3K/Akt pathways to regulate cell adhesion and inflammation [245] and suppressing TGF-1 signaling, which is central to fibroblast-to-myofibroblast differentiation and the progression of fibrosis [19]

Role of the autonomic nervous system in atrial fibrillation: pathophysiology and therapy