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Additionally, the TRPM8 gene, which responds to cold stimuli, has been linked to an increased risk of chronic migraine in individuals carrying the TRPM8 rs10166942 T allele (Ling et al., 2019)

Miller-Fleming L, Olin-Sandoval V, Campbell K, et al

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Curr Med Chem 11:11351146 Reznick RM, Shulman GI (2006) The role of AMP-activated protein kinase in mitochondrial biogenesis

