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Xiaolan Z, Jin Lin W, John L, Yanping S, Kwak KS, Qingsheng J, Robert R, Qing C, Thomas B

Research on L-Carnitine

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B cells play dual roles in diet-induced NAFLD by secreting cytokines and antibodies, a phenomenon that was reviewed in a recent literature report [134]

Integrin receptors within the stromal extracellular matrix (ECM) are critical in this regard,133,147 as they constitute the first point of contact for disseminating cancer cells, permitting adhesion to the pre-metastatic niche.148 Cancer-associated fibroblasts (CAFs) define ECM composition and promote tumour progression by regulating integrins and signalling pathways such as TGF-.149 Nevertheless, the precise mechanisms by which the ECM governs cancer-cell dormancy remain to be elucidated