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The frequency depends on your B12 levels and medical history
Studies have shown that DCs are primarily found in synovial fluid, mainly as mature cDCs (conventional DCs derived from myeloid stem cells) and immature pDCs (plasmacytoid DCs derived from lymphoid stem cells), and play a unique role in cartilage damage (102)
If you just go and take regular calcium carbonate, magnesium carbonate, magnesium oxide, that has some benefit, but it doesnt get into the brain
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