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Ultrahigh-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry (UHPLC-Q-TOF/MS, Waters Corp., Milford, United States) was used for sample analysis

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Further, the difference in the accumulation profile was analyzed across a range of physicochemical parameters, including hydrogen bonding numbers, rotatable bonds, molecular weight, topological polar surface area, ClogP, and logS (Fig

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Consequently, hypoxic cells compensate by either (i) scavenging unsaturated fatty acidspreferentially from lysophospholipidsto maintain membrane homeostasis