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Selenium-containing GPX4 is important for living cell to allow the utilization of biomembranes for increased cellular plasticity and for the utilization of peroxides as second messengers in redox signaling processes [115, 116]

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The results showed that APG-157 achieved measurable levels of curcuminoids in oral tissues and blood, confirming systemic absorption from oral delivery

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Iron(III) acetylacetonate (Fe(acac) 3 ), chloro(protoporphyrinato)iron(III) (hemin), L-Glutathione reduced (GSH), L-Glutathione oxidized (GSSG) and N,N-Diisopropylethylamine (DIEA) were purchased from Sigma-Aldrich

The results showed that the detection limits for acetaminophen and ofloxacin were 3*10 8 M and 8*10 9 M, respectively
