glutathione s transferase pgex Impact of Oxidative Changes and Possible Effects of Genetics Polymorphisms of S-Transferase in Diabetics Patients with Complications The role of glutathione S-transferases

10.1016/S0896-6273(01)00517-7 [DOI] [PubMed] [Google Scholar] Fujita W., Gomes I., Devi L

Evidence caveat: The combination approach is based on clinical observation and mechanistic reasoning, not controlled trials

3.3 Glutamate dehydrogenase (GLUD/GDH) inhibitors Glutamine is enzymatically converted to glutamate by glutaminase, and further conversion of glutamate to -KG is facilitated by GLUD through oxidative deamination (Yoo et al., 2020)

Important: Kojic acid may increase skin sensitivity

Although the multi-target characteristics of natural products can decrease drug resistance, they complicate mechanistic studies

Part of her daily routine Khanyi's skin lightening process is done once a week and she said it takes about 20 minutes to do the treatment