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PMID: 42140913 Nat CommunThe UFL1-AKT positive feedback loop promotes breast cancer progression by enhancing lipid synthesis

10.1074/jbc.M212307200 Chavez JA, Holland WL, Bar J, Sandhoff K, Summers SA: Acid ceramidase overexpression prevents the inhibitory effects of saturated fatty acids on insulin signaling

Current evidence is exploratory, emphasizing the need for further investigation before establishing definitive interpretations

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for instance, its not known to affect how other drugs are metabolized or to block their action

Pfeffer 2019
