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If 8mg weekly produces excellent results with minimal side effects, there may be no benefit to pushing to 12mg if doing so causes substantial discomfort

Experimental investigations have reported effects on VEGFR2 phosphorylation, focal adhesion kinase (FAK) activation, ERK1/2 signaling, and nitric oxide-associated regulatory pathways

[DOI] [PubMed] [Google Scholar] 35.Torgerson JS, Hauptman J, Boldrin MN, Sjstrm L

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It is not approved as a medicine in any country
