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Landreh, M

GSH exists as the biologically active reduced-thiol form, and its oxidation to GSSG is associated with oxidative stress (OS)

Levels of tGSH in the TIF were much higher than reported amounts added to formulations of cell culture media (Extended Data Fig

doi: 10.3389/fphar.2021.640185

In contrast to males, female PD- LRRK2 patients showed fewer dysregulated pathways, including serine, glycine, cysteine, methionine, and betaine metabolism, amino sugar and pyruvate metabolism, phosphatidylethanolamine and fatty acid biosynthesis, as well as mitochondrial-related dysregulation of acetyl group transfer pathways ( Fig