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J.LuijendijkI.BouquetJ.SinaasappelM

While numerous synthetic ARIs have demonstrated excellent inhibition and shown promising results in animal studies, their efficacy in clinical trials was not very encouraging with some ARIs exhibiting adverse side effects

The significant roles of SOD and CAT in antioxidant defense and ferroptosis suppression also highlight the therapeutic potential of combining antioxidants with ferroptosis inhibitors

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Scand J

Substitution of Met 123 with cysteine in CnrX abolishes Ni(II)-responsive expression and decreases the Co(II)-affinity by ~2000-fold [120]