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It was first described in the Journal of Physiology-Paris by Sikiri and colleagues in 1993

Clinical research has shown BPC-157s benefits for mental, gastrointestinal, cardiac, and autoimmune health

Andersen CB, Madsen M, Storm T, Moestrup SK, Andersen GR (2010) Structural basis for receptor recognition of vitamin-B(12)-intrinsic factor complexes

The Institute of Medicine reports mixed results on whether smokers excrete more B12 than nonsmokers, but concludes that the effect of smoking on B12 requirements appears to be negligible (IOM, 1998)

Trani, E

Once a dog has begun taking a vitamin B12 supplement, small improvements may be seen in just a few days, but it can take several weeks before the dog fully responds to treatment.