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We showed that inherent anxiety at baseline and elevated expression of the mineralocorticoid receptors (MR) in the hippocampus predisposes to a stress-induced suppression of expression of metabotropic glutamate receptors-2 (mGlu2, a key inhibitor of spontaneous glutamate release) with development of depressive-like behavior via epigenetic mechanisms of histone acetylation [20]

Higher levels of Zonulin-1 (ZO-1) reflect compromised intestinal lining integrity

Notably, the direct oxidation of medium-chain fatty acids (MCFAs) is still a controversial issue

Friedreichs Ataxia: Clinical Features, Pathogenesis and Management

The crushing fatigue, the unpredictable post-exertional crashes, and the disorienting brain fog are not manifestations of anxiety or a lack of willpower