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These effects result from the peptide's ability to activate multiple growth factor pathways simultaneously, including TGF-, basic fibroblast growth factor (bFGF), and insulin-like growth factor-1 (IGF-1)

Keratinocyte migration assays showed 2-3-fold increases with concentrations as low as 10 picograms of TB-500

However, systemic subcutaneous protocols typically use the ranges above

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