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Mechanistically, TSA ME upregulated H3K18ac and H4K8ac expression, downregulated excitotoxicity-related NMDAR1 protein and apoptosis-related Caspase-3 and concurrently promoted neuronal cytoskeletal protein MAP-2 expression (210)

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Treatment with Fer-1, Lip-1, or neural stem cell-derived extracellular vesicles enriched in CDC42 substantially attenuates cerebrovascular damage and cognitive deficits in PD mice (Li et al., 2025b)

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Slides were mounted using ProLong Antifade with DAPI (Life Technologies)

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