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Inflammatory conditions are often exacerbated by dysregulated non-coding RNA networks and immune cell polarization, as seen in chronic diseases where exosomal lncRNAs such as MEG3 can drive M1 macrophage polarization and pyroptosis through pathways involving TREM-1 (24)

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These studies exclusively examined the efficacy of specific probiotic strains in reducing the risk of atopic eczema in children