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Furthermore, oxidized LDL has been shown to upregulate oxidized LDL receptor-1 (LOX-1) expression in endothelial cells which results in endothelial dysfunction by inducing apoptosis and inflammation [274]

Konopleva M, Zhao S, Jiang S, Snell V, Zhang X, Reed JC, Andreeff M

There were also positive correlations between the total intensity of reversibly oxidised Cys and the ratio of GSSG/GSH in ALS patients for both visits ( P = 0.0193 and 0.0367, respectively)

Crucially, honeys apoptotic effects are concentration- and time dependent

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doi: 10.1016/j.mam.2020.100889 28 ZhaoSChenFYinQWangDHanWZhangY