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Its main active ingredient is an active form of vitamin B3, but the emphasis here is on its highly pure nature

B., and Mahfouz M

[DOI] [PMC free article] [PubMed] [Google Scholar] 84.Giacco F., Brownlee M

for example, PKM2 activates the HIF-1 transcription factor by modulating ATP levels required for tumor cell proliferation, thereby promoting glycolysis

In cases where oxidative stress is the pathophysiological basis, some natural antioxidant products work through different mechanisms than conventional drugs do to enhance therapeutic efficacy, avoiding the need to add new drugs to basal therapies, thus achieving therapeutic goals at lower doses of standard therapies (191)