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The inclusion and exclusion criteria were defined in direct accordance with the PICOS framework
Public Health Division of the Welsh Government reply We have received a reply from the Public Health Division of the Welsh Government re-assuring us that stocks of vitamin B12 injections are not affected by the current situation with COVID-19, and that when a patients has made an appointment, an assessment needs to be made on the day to determine whether the patient has any of the symptoms of infection
As the glucose is excreted there is a concomitant loss of water to maintain normal osmolarity of the urine
Additionally, stress, smoking, certain health conditions and a deficiency in essential nutrients can contribute to the premature loss of hair colour
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