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Frequently asked questions Early warning signs of B12 deficiency include unexplained fatigue, tingling or numbness in your hands and feet, difficulty concentrating, and mood changes

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Upon approval of the physician, medications are shipped out

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Importantly, persistently high serum B12 in the absence of supplementation should prompt GP assessment, as it may indicate underlying disease processes

While very high oral doses (1,000 to 2,000 mcg) can achieve some passive absorption without intrinsic factor roughly 1% of the dose is absorbed passively many clinicians prefer the reliability and rapid correction offered by injections in this population