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Description
In a supplement containing 50 mcg of Vitamin B12, you absorb about 1.5 mcg of thatand only 0.1 to 0.6 mcg if you have a problem with absorption or have pernicious (autoimmune) anemia

So injecting beyond a certain point may cause your cells to fight off the excess B12 so hard that it might reduce the amount of active cellular B12 - probably not to dangerous levels, but possibly sufficient to trigger some symptoms
But whats in them

Research-only escalation preview This preview illustrates how study participants were escalated from lower starting doses up to their final weekly dose

For info: In the FDA report published in December, the most common side effects were pain at injection site (91.6% of patients), fatigue (68.5%), headache (63.0%), muscle pain (59.6%), joint pain (44.8%), and chills (43.4%)

Potential side effects & safety considerations Due to limited available data, assessing 5-Amino-1MQ side effects is challenging
