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Due to the intrinsic characteristics of KRAS proteins, targeting KRAS has been considered to be quite challenging

E.De DalyM

Endocr Rev 19 : 269301

A recent study has examined the effect of cobalamin supplementation on the outcomes of treatment for feline patients with severe cobalamin deficiency and histories suggesting chronic gastrointestinal disease.5 In this study, serum concentrations of methylmalonic acid normalized following parenteral cobalamin supplementation, indicating that cobalamin deficiency was the cause of the high methylmalonic acid in serum

J.S, M.B., and E.T

Among the different drug delivery systems (DDSs), polymeric nanoparticles, mesoporous silica nanoparticles (MSNs), and liposomes are frequently employed