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Eur Arch Otorhinolaryngol 282 , 37573769 (2025)

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An additional difficulty in diagnosing cobalamin deficiency occurs in patients taking oral vitamin B12 supplementation who do not have absorption disorders

The unique binding sites of isatuximab and daratumumab may explain their differential in vitro abilities to inhibit the CD38 enzymatic activity and to induce different structural changes within the CD38 molecule upon binding
