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MTHFR mutations are commonly associated with high homocysteine levels 3 and low methionine production, which in turn may lead to the accumulation of S-adenosylhomocysteine (SAH) and low levels of SAMe

doi: 10.1016/S0168-8278(99)80128-7

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Pediatrics 145 , e20192316 (2020)

[DOI] [PMC free article] [PubMed] [Google Scholar] 211.Zhang X., Howell G.M., Guo L., Collage R.D., Loughran P.A., Zuckerbraun B.S., Rosengart M.R

Donor compartments received 3-PLG-dopa or 3-PLG-dopa-A-GSH (100 g/ml) diluted in phenol red-free DMEM/HAMs F-12 medium supplemented with 5% FBS and the model was incubated for 24 h