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Specifically, we measured mouse signal-regulatory protein alpha (SIRP) (three Ig domains), mouse E-cadherin (five cadherin domains), and human carcinoembryonic antigen related cell adhesion molecule 5 (CEACAM5) full-length protein (seven Ig-like domains), as well as the N-terminal domain of CEACAM5 alone (one Ig-like domain)

acknowledges support from the National Institutes of Health (NIH) (P50CA272218) and the Melanoma Research Foundation

ALCAR downregulates pro-inflammatory cytokine/chemokine involved in PCa and BPH cells Evidence from the clinic indicates that prostate cancer progression correlates with elevated inflammation [3, 8,9,10,11, 37, 38]