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Description
A.DemchenkoK
Inhibition of Gln, when combined with radiotherapy, triggers ferroptosis in immunogenic tumors
Among these inhibitors were BH3 mimetics including Venetoclax and Navitoclax, two molecules widely used for the treatment of MDS and AML
Currently, no small-molecule drug targeting GSTO1 is under clinical development
Science (2019) 364:9605
Fact: No human evidence demonstrates a dose-response relationship
