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Keywords: chondrocyte, senescence, autologous chondrocyte implantation, senolytic, FOXO4-DRI Introduction Autologous chondrocyte implantation (ACI) is a biomedical treatment that repairs cartilage injury in the knee joint, which has been shown to reduce pain and facilitate mobility recovery (Kreuz et al., 2019)

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Potential Benefits: Muscle Growth and Performance: Enhances muscle mass and overall physical performance through increased cellular growth and regeneration

In laboratory studies, DSIP has been explored for its effects on stress-related signaling, hormonal balance, and neural recovery during sleep cycles

Quaife-Ryan et al