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[DOI] [PubMed] [Google Scholar] 144.Bykztrk A.l., Kant L., Ersz B., Mente G., Hariri N.

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Evidence show berberine recovers DSS-induced UC in a microbial-dependent manner, with it maintaining the structure and function of the intestinal mucosal barrier, regulating intestinal mucosal immune homeostasis, activating Wnt/-catenin pathway, 521 FXR/TGR5 signaling, increasing unconjugated bile acids and secondary bile acids in the gastrointestinal tract, 522 activating aromatic hydrocarbon receptors 523 to exert its protective effect in the colon

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doi: 10.1084/jem.20211314

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