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NLRP3 inflammasome is formed due to hyperglycaemia and hyperlipidaemia, which promote pro-inflammatory cytokines by upregulating IL-1, IL-6 and IL-18, leading towards exacerbation of DCM pathology (134)

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Cancer drug resistance related microRNAs: recent advances in detection methods

In recent years, cybrid models have continued to shed light on mitochondrial dysfunction in various pathologies, including drug-induced liver disease

AMY receptors and GLP-1 receptors share Gs coupling at the second-messenger level, but their tissue-distribution profiles, downstream effector specificity, and ligand-binding pockets are pharmacologically distinct

Each item was scored 0, 1 or 2 according to the severity, with differential weighting according to the relevance of these variables