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doi:10.1007/5584_2016_121 Mi Y, Yan S, Lu Y, Liang Y, Li C

Recent regulatory commentary in 2025 emphasized that clinics offering B12 injections should ensure appropriate screening and physician oversight

As noted by Kraus et al., Nature Medicine and Ng et al., Journal of Endocrinology , targeting both systemic metabolism and localized fat cell activity may enhance fat-loss outcomes beyond either approach alone

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Ultrapure water (18.2 M cm resistivity, Arium Comfort H2O-I-1-UV-T from Sartorius, Goettingen, Germany) or LC-MS grade water (LiChrosolv, Merck KGaA) was used throughout