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Hippocampal pdha1 gene knockout inhibits the warburg effect leading to cognitive dysfunction and attenuates the beneficial effects of zibupiyin recipe on cognition

Here, we review data on mouse strains with alterations in the GH/IGF-1 axis and their effects on lifespan

Limonene acts as an antioxidant, meaning it helps neutralize free radicals

Ultimately, this review proposes that PEM may arise from a complex interplay among mitochondrial dysfunction, immune activation, and neuroinflammation, which together form a self-perpetuating loop of energy exhaustion - inflammation amplification, potentially contributing to the chronic and multi-system nature of PEM symptoms

In a case-control study with NASH patients, a positive correlation was found between the increase in Se levels and the GSH/GSSG ratio

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