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Nevertheless, both butyrate and propionate modulate the ENS through three principal mechanisms: Firstly, neurotransmitter modulation: SCFAs balance excitatory and inhibitory signals in the ENS by modulating certain neurotransmitters

10.1186/s13098-023-01174-y 123 LiX.LiC.ZhangW.WangY.QianP.HuangH

In reference to proteins, the term "topographically shaped" refers to the polypeptide-based structural representation of a protein located within a defined protein space

While 23% weight loss is clinically meaningful, failing non-inferiority in a head-to-head setting underscores the rising competitive bar

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