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Biological variability across cancer subtypes and patient characteristics further complicates interpretation

PLP is also required for glycogen homeostasis as a cofactor for glycogen phosphorylase

[DOI] [PMC free article] [PubMed] [Google Scholar] Gao L, Kim KJ, et al
Activated IGF-1R can stabilize integrins and promote epithelial mesenchymal transition (EMT), which, in cancer, can contribute to subsequent progression to metastatic disease [30]
Gill AJ, Garza R, Ambegaokar SS et al (2018) Heme oxygenase-1 promoter region (GT)n polymorphism associates with increased neuroimmune activation and risk for encephalitis in HIV infection

Immunity 2013
