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We measured the time from the onset of heat stimulation to the observation of the withdrawal reflex (Figure 2Aiii)

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While there are several drugs approved by the US Food and Drug Administration for treating AD, the most commonly used medications to address the cognitive impairments experienced by AD patients include three acetylcholinesterase (AchE) inhibitors (galantamine, rivastigmine, donepezil) and one N-Methyl-D-Aspartate (NMDA) receptor antagonist (memantine)