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Analysis of a purified chloroplast protein produced similar values, although with a somewhat higher affinity for GSH (Shimaoka et al., 2000)

Nat Commun 13 , 920 (2022)

2 CHAC1 as a central integrator of glutathione homeostasis, stress signaling and ferroptosis Glutathione homeostasis is essential for cellular and organismal health due to its central role in maintaining redox balance

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Patients either received 15 mg twice-daily IN-NAP or placebo for a period of 12 weeks, with limited adverse events noted (i.e., headache) and a cognitive battery carried out at baseline and after 4, 8, 12, and 16 weeks of IN treatment [108,109]

As mentioned, in the brain, these genes regulate a variety of biological processes involved in the physiology of sleep and its disturbances (Sandberg et al