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Description
A lack of energy can also disrupt these mechanisms

Rapid weight loss, as can occur with potent GLP-1 receptor agonists, may result in loss of both fat and lean tissue

The difference between A 142 and A 140 lies in the subtle addition of an isoleucine and an alanine at the c-terminus of A 142 that greatly affect its propensity to aggregate

Therefore, it is urgently necessary to clarify the core influencing factors that regulate the direction of its effects

Nature 552 (7684), 194199

doi: 10.1016/j.cclet.2023.108946
